Lead vocal
Eric Clapton
Microphone
Neumann U 87
ReportedMicrophone Clapton sang the lead vocal into while overdubbing it in the live room over several nights.
Source: Sound On Sound, accessed 15 Nov 2026
Input chain
UREI 1176
ReportedCompressor applied to the comped lead vocal.
Source: Sound On Sound, accessed 15 Nov 2026
Emulation of this unit
Universal Audio 1176 Classic Limiter Collection
compressor
Models several revisions of the 1176, including the blackface units.
Also worth a look: Waves CLA-76 Compressor / Limiter (Models two 1176 revisions (blacky and bluey)).
Guitars
Eric Clapton and Duane Allman
Amplifier
Fender Champ (Tweed)
VerifiedSmall amps used by both Clapton and Allman, kept low in volume and placed on the closed piano to help isolate them from the drums and piano.
- Position
- On top of the closed piano lid
Source: Sound On Sound, accessed 15 Nov 2026
Covers this kind of unit
IK Multimedia AmpliTube 5
amp and cabinet simulator
An amp and cabinet simulator that covers a wide range of amplifiers and speaker cabinets of this kind. It is not a model of this unit, so pick the nearest one in it by ear.
Also worth a look: Native Instruments Guitar Rig 7 Pro (An amp and cabinet simulator that covers a wide range of amplifiers and speaker cabinets of this kind. It is not a model of this unit, so pick the nearest one in it by ear).
Album sessions, not stated for this song: Rotating-speaker cabinet for guitar that Clapton loved and the studio used a lot across the sessions; pedals switched it and its rotor on and off.
- Settings
- Motor speed set by a large Variac, run neither too fast nor too slow so the pedal gave a start-stop effect
Source: Sound On Sound, accessed 15 Nov 2026
Covers this kind of unit
IK Multimedia AmpliTube 5
amp and cabinet simulator
An amp and cabinet simulator that covers a wide range of amplifiers and speaker cabinets of this kind. It is not a model of this unit, so pick the nearest one in it by ear.
Also worth a look: Native Instruments Guitar Rig 7 Pro (An amp and cabinet simulator that covers a wide range of amplifiers and speaker cabinets of this kind. It is not a model of this unit, so pick the nearest one in it by ear).
Microphone
Shure SM57
ReportedUsed on the guitar amps, in combination with Electrovoice 635s.
Source: Sound On Sound, accessed 15 Nov 2026
Electro-Voice 635
ReportedUsed on the guitar amps, in combination with Shure SM57s.
Source: Sound On Sound, accessed 15 Nov 2026
Bass
Carl Radle
Amplifier
Recorded direct (DI), no amplifier
ReportedRadle bass recorded direct.
Source: Sound On Sound, accessed 15 Nov 2026
Drum kit
Jim Gordon
Microphone
Neumann U 47
ReportedPair of microphones used as overheads.
Source: Sound On Sound, accessed 15 Nov 2026
Altec 633 Salt Shaker
ReportedMicrophone on the bass drum.
Source: Sound On Sound, accessed 15 Nov 2026
Keyboards
Bobby Whitlock and Jim Gordon
Microphone
Shure SM57
ReportedMicrophones on Whitlock's Hammond B3 Leslie speaker.
- Position
- A couple at the top of the Leslie and another at the bottom
Source: Sound On Sound, accessed 15 Nov 2026
AKG 414 (variant not stated)
VerifiedMicrophones put inside the piano so the guitarists could hear it, with the lid closed and the piano covered in quilts and gaffer tape.
- Position
- Inside the piano, on foam
Source: Sound On Sound, accessed 15 Nov 2026
Console and effects
Input chain
Console the track was recorded on, in Criteria Studio B.
Source: Sound On Sound, accessed 15 Nov 2026
Covers this kind of unit
Metric Halo MBSI Channel Strip
channel strip
Models the channel strip of a custom MCI desk built for Criteria Studios in the 1970s, so it is the same maker's sound. It is not a model of the desk on the record.
Mix effects
EMT Echo (model not stated)
ReportedOne of the only effects on the track, alongside tape loops.
Source: Sound On Sound, accessed 15 Nov 2026
Covers this kind of unit
Universal Audio EMT 140 Classic Plate Reverberator
reverb
Models the EMT 140 plate, the firm's best-known reverb. The source does not name the model, so this stands for the maker's family of units: it is not a model of the one on the record.
Also worth a look: Soundtoys Little Plate (A simple plate reverb based on the EMT 140, the firm's best-known reverb. The source does not name the model, so this stands for the maker's family of units: it is not a model of the one on the record).
Sources
- Classic Tracks: Derek & The Dominos 'Layla', Sound On Sound, 2006-09. Accessed 15 Nov 2026.
Stated by the engineer, producer or artist, or by the manufacturer.
Stated by a reputable secondary source.
An educated suggestion, not a documented fact.
Disclosure: plugin links currently go straight to the maker and earn us nothing. If that changes, affiliate links will be marked here. Suggestions are chosen on fit, never on commission, and are kept separate from the recording facts. More.